To play Itzi, first shuffle the letter cards and clue cards. Each player gets a set of letter cards. The goal is to be the first to match the right letter cards to the right clue cards. There are many different ways to play, so you can mix it up for more fun. When you're done playing, keep the cards in a dry and cool place to prevent damage. Don't bend or tear the cards. If they get dirty, you can gently wipe them with a soft cloth. Enjoy playing Itzi with your friends and family!